2o8e: Difference between revisions

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{{Seed}}
[[Image:2o8e.png|left|200px]]
[[Image:2o8e.png|left|200px]]


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{{STRUCTURE_2o8e|  PDB=2o8e  |  SCENE=  }}  
{{STRUCTURE_2o8e|  PDB=2o8e  |  SCENE=  }}  


===human MutSalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 only===
===human MutSalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 only===


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{{ABSTRACT_PUBMED_17531815}}
{{ABSTRACT_PUBMED_17531815}}
==Disease==
Known disease associated with this structure: Colorectal cancer, hereditary nonpolyposis, type 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=609309 609309]], Mismatch repair cancer syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=609309 609309]], Muir-Torre syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=609309 609309]]


==About this Structure==
==About this Structure==
2O8E is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8E OCA].  
[[2o8e]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8E OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:17531815</ref><references group="xtra"/>
<ref group="xtra">PMID:017531815</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Beese, L S.]]
[[Category: Beese, L S.]]
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[[Category: Abc transporter atpase]]
[[Category: Abc transporter atpase]]
[[Category: Cancer]]
[[Category: Cancer]]
[[Category: Dna binding protein-dna complex]]
[[Category: Dna damage response]]
[[Category: Dna damage response]]
[[Category: Dna mismatch repair]]
[[Category: Dna mismatch repair]]
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[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
[[Category: Somatic hypermutation]]
[[Category: Somatic hypermutation]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:31:52 2009''
Retrieved from "https://proteopedia.org/2o8e"