1w39: Difference between revisions
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New page: left|200px<br /><applet load="1w39" size="450" color="white" frame="true" align="right" spinBox="true" caption="1w39, resolution 3.75Å" /> '''CRYSTAL STRUCTURE OF... |
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[[Image:1w39.gif|left|200px]]<br /><applet load="1w39" size=" | [[Image:1w39.gif|left|200px]]<br /><applet load="1w39" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1w39, resolution 3.75Å" /> | caption="1w39, resolution 3.75Å" /> | ||
'''CRYSTAL STRUCTURE OF AN ARTIFICIAL TOP COMPONENT OF TURNIP YELLOW MOSAIC VIRUS'''<br /> | '''CRYSTAL STRUCTURE OF AN ARTIFICIAL TOP COMPONENT OF TURNIP YELLOW MOSAIC VIRUS'''<br /> | ||
==Overview== | ==Overview== | ||
Empty capsids (artificial top component) of turnip yellow mosaic virus | Empty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection. | ||
==About this Structure== | ==About this Structure== | ||
1W39 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http:// | 1W39 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W39 OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Turnip yellow mosaic virus]] | [[Category: Turnip yellow mosaic virus]] | ||
[[Category: Abrahams, J | [[Category: Abrahams, J P.]] | ||
[[Category: Bink, H | [[Category: Bink, H H.J.]] | ||
[[Category: Pannu, N | [[Category: Pannu, N S.]] | ||
[[Category: Plaisier, J | [[Category: Plaisier, J R.]] | ||
[[Category: Pleij, C | [[Category: Pleij, C W.A.]] | ||
[[Category: Roon, A | [[Category: Roon, A M.M Van.]] | ||
[[Category: artificial top component]] | [[Category: artificial top component]] | ||
[[Category: capsid protein]] | [[Category: capsid protein]] | ||
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[[Category: virus/viral protein]] | [[Category: virus/viral protein]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:40:00 2008'' | ||