2itk: Difference between revisions

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{{Seed}}
[[Image:2itk.png|left|200px]]
[[Image:2itk.png|left|200px]]


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{{STRUCTURE_2itk|  PDB=2itk  |  SCENE=  }}  
{{STRUCTURE_2itk|  PDB=2itk  |  SCENE=  }}  


===human Pin1 bound to D-PEPTIDE===
===human Pin1 bound to D-PEPTIDE===


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{{ABSTRACT_PUBMED_17518432}}
{{ABSTRACT_PUBMED_17518432}}


==About this Structure==
==About this Structure==
2ITK is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITK OCA].  
[[2itk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ITK OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:17518432</ref><references group="xtra"/>
<ref group="xtra">PMID:017518432</ref><ref group="xtra">PMID:021980916</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Peptidylprolyl isomerase]]
Line 29: Line 17:
[[Category: Zhang, Y.]]
[[Category: Zhang, Y.]]
[[Category: Isomerase]]
[[Category: Isomerase]]
[[Category: Isomerase-isomerase inhibitor complex]]
[[Category: Pin1]]
[[Category: Pin1]]
[[Category: Ww domain]]
[[Category: Ww domain]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:25:40 2009''

Revision as of 12:02, 7 January 2013

File:2itk.png

Template:STRUCTURE 2itk

human Pin1 bound to D-PEPTIDE

Template:ABSTRACT PUBMED 17518432

About this Structure

2itk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Zhang Y, Daum S, Wildemann D, Zhou XZ, Verdecia MA, Bowman ME, Lucke C, Hunter T, Lu KP, Fischer G, Noel JP. Structural basis for high-affinity peptide inhibition of human Pin1. ACS Chem Biol. 2007 May 22;2(5):320-8. PMID:17518432 doi:https://dx.doi.org/10.1021/cb7000044
  2. Xu GG, Zhang Y, Mercedes-Camacho AY, Etzkorn FA. A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state. Biochemistry. 2011 Nov 8;50(44):9545-50. Epub 2011 Oct 18. PMID:21980916 doi:10.1021/bi201055c

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