3clx: Difference between revisions

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Revision as of 18:08, 7 January 2013

File:3clx.png

Template:STRUCTURE 3clx

Crystal structure of XIAP BIR3 domain in complex with a Smac-mimetic compound, Smac005

Template:ABSTRACT PUBMED 18851976

About this Structure

3clx is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Mastrangelo E, Cossu F, Milani M, Sorrentino G, Lecis D, Delia D, Manzoni L, Drago C, Seneci P, Scolastico C, Rizzo V, Bolognesi M. Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo[5.3.0]alkane smac mimetics. Structure, activity, and recognition principles. J Mol Biol. 2008 Dec 19;384(3):673-89. Epub 2008 Oct 7. PMID:18851976 doi:10.1016/j.jmb.2008.09.064

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