3cqw: Difference between revisions

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{{Seed}}
[[Image:3cqw.png|left|200px]]
[[Image:3cqw.png|left|200px]]


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{{STRUCTURE_3cqw|  PDB=3cqw  |  SCENE=  }}  
{{STRUCTURE_3cqw|  PDB=3cqw  |  SCENE=  }}  


===Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor===
===Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor===


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{{ABSTRACT_PUBMED_18456494}}
{{ABSTRACT_PUBMED_18456494}}


==About this Structure==
==About this Structure==
3CQW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQW OCA].  
[[3cqw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CQW OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:18456494</ref><references group="xtra"/>
<ref group="xtra">PMID:018456494</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Pandit, J.]]
[[Category: Pandit, J.]]
[[Category: Alternative splicing]]
[[Category: Apoptosis]]
[[Category: Apoptosis]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Carbohydrate metabolism]]
[[Category: Carbohydrate metabolism]]
[[Category: Cytoplasm]]
[[Category: Glucose metabolism]]
[[Category: Glucose metabolism]]
[[Category: Glycogen biosynthesis]]
[[Category: Glycogen biosynthesis]]
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[[Category: Transport]]
[[Category: Transport]]
[[Category: Wnt signaling pathway]]
[[Category: Wnt signaling pathway]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:00:53 2009''

Revision as of 18:17, 7 January 2013

File:3cqw.png

Template:STRUCTURE 3cqw

Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor

Template:ABSTRACT PUBMED 18456494

About this Structure

3cqw is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Lippa B, Pan G, Corbett M, Li C, Kauffman GS, Pandit J, Robinson S, Wei L, Kozina E, Marr ES, Borzillo G, Knauth E, Barbacci-Tobin EG, Vincent P, Troutman M, Baker D, Rajamohan F, Kakar S, Clark T, Morris J. Synthesis and structure based optimization of novel Akt inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3359-63. Epub 2008 Apr 15. PMID:18456494 doi:10.1016/j.bmcl.2008.04.034

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