3bg9: Difference between revisions

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{{Seed}}
[[Image:3bg9.png|left|200px]]
[[Image:3bg9.png|left|200px]]


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{{STRUCTURE_3bg9|  PDB=3bg9  |  SCENE=  }}  
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===Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus) F1077A Mutant===
===Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus) F1077A Mutant===


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{{ABSTRACT_PUBMED_18297087}}
{{ABSTRACT_PUBMED_18297087}}
==Disease==
Known disease associated with this structure: Pyruvate carboxylase deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608786 608786]], Thrombophilia due to protein C deficiency, autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612283 612283]], Thrombophilia due to protein C deficiency, autosomal recessive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=612283 612283]]


==About this Structure==
==About this Structure==
3BG9 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BG9 OCA].  
[[3bg9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BG9 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:18297087</ref><references group="xtra"/>
<ref group="xtra">PMID:018297087</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Pyruvate carboxylase]]
[[Category: Pyruvate carboxylase]]
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[[Category: Tim barrel]]
[[Category: Tim barrel]]
[[Category: Transit peptide]]
[[Category: Transit peptide]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:38:39 2009''

Revision as of 18:27, 7 January 2013

File:3bg9.png

Template:STRUCTURE 3bg9

Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus) F1077A Mutant

Template:ABSTRACT PUBMED 18297087

About this Structure

3bg9 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Xiang S, Tong L. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat Struct Mol Biol. 2008 Mar;15(3):295-302. Epub 2008 Feb 24. PMID:18297087 doi:10.1038/nsmb.1393

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