2r43: Difference between revisions
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[[Image:2r43.png|left|200px]] | [[Image:2r43.png|left|200px]] | ||
{{STRUCTURE_2r43| PDB=2r43 | SCENE= }} | {{STRUCTURE_2r43| PDB=2r43 | SCENE= }} | ||
===I50V HIV-1 protease in complex with an amino decorated pyrrolidine-based inhibitor=== | ===I50V HIV-1 protease in complex with an amino decorated pyrrolidine-based inhibitor=== | ||
{{ABSTRACT_PUBMED_18692068}} | {{ABSTRACT_PUBMED_18692068}} | ||
==About this Structure== | ==About this Structure== | ||
[[2r43]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R43 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018692068</ref><references group="xtra"/> | ||
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
| Line 33: | Line 21: | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Protein-ligand complex]] | [[Category: Protein-ligand complex]] | ||
Revision as of 18:44, 7 January 2013
I50V HIV-1 protease in complex with an amino decorated pyrrolidine-based inhibitor
Template:ABSTRACT PUBMED 18692068
About this Structure
2r43 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Bottcher J, Blum A, Heine A, Diederich WE, Klebe G. Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 protease. J Mol Biol. 2008 Nov 7;383(2):347-57. Epub 2008 Jul 29. PMID:18692068 doi:10.1016/j.jmb.2008.07.062
