3cas: Difference between revisions

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{{Seed}}
[[Image:3cas.png|left|200px]]
[[Image:3cas.png|left|200px]]


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{{STRUCTURE_3cas|  PDB=3cas  |  SCENE=  }}  
{{STRUCTURE_3cas|  PDB=3cas  |  SCENE=  }}  


===Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione===
===Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione===


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{{ABSTRACT_PUBMED_19075558}}
{{ABSTRACT_PUBMED_19075558}}


==About this Structure==
==About this Structure==
3CAS is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CAS OCA].  
[[3cas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CAS OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:19075558</ref><references group="xtra"/>
<ref group="xtra">PMID:019075558</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Breton, R]]
[[Category: Breton, R]]
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[[Category: Androstenedione]]
[[Category: Androstenedione]]
[[Category: Bile acid catabolism]]
[[Category: Bile acid catabolism]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Lipid metabolism]]
[[Category: Lipid metabolism]]
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[[Category: Steroid metabolism]]
[[Category: Steroid metabolism]]
[[Category: Substrate inhibition]]
[[Category: Substrate inhibition]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 11:23:47 2010''

Revision as of 19:11, 7 January 2013

File:3cas.png

Template:STRUCTURE 3cas

Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione

Template:ABSTRACT PUBMED 19075558

About this Structure

3cas is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Faucher F, Cantin L, Luu-The V, Labrie F, Breton R. Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition. Biochemistry. 2008 Dec 23;47(51):13537-46. PMID:19075558 doi:10.1021/bi801276h

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