2xh5: Difference between revisions

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===STRUCTURE OF 4-(4-TERT-BUTYLBENZYL)-1-(7H-PYRROLO(2,3-D) PYRIMIDIN-4-YL)PIPERIDIN-4-AMINE BOUND TO PKB===
===STRUCTURE OF 4-(4-TERT-BUTYLBENZYL)-1-(7H-PYRROLO(2,3-D) PYRIMIDIN-4-YL)PIPERIDIN-4-AMINE BOUND TO PKB===


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{{ABSTRACT_PUBMED_20151677}}


==About this Structure==
==About this Structure==
2XH5 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2x37 2x37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XH5 OCA].  
[[2xh5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2x37 2x37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XH5 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20151677</ref><references group="xtra"/>
<ref group="xtra">PMID:020151677</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
Line 50: Line 38:
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Wnt signaling pathway]]
[[Category: Wnt signaling pathway]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:33:55 2010''

Revision as of 19:26, 7 January 2013

File:2xh5.png

Template:STRUCTURE 2xh5

STRUCTURE OF 4-(4-TERT-BUTYLBENZYL)-1-(7H-PYRROLO(2,3-D) PYRIMIDIN-4-YL)PIPERIDIN-4-AMINE BOUND TO PKB

Template:ABSTRACT PUBMED 20151677

About this Structure

2xh5 is a 2 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2x37. Full crystallographic information is available from OCA.

Reference

  1. McHardy T, Caldwell JJ, Cheung KM, Hunter LJ, Taylor K, Rowlands M, Ruddle R, Henley A, de Haven Brandon A, Valenti M, Davies TG, Fazal L, Seavers L, Raynaud FI, Eccles SA, Aherne GW, Garrett MD, Collins I. Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt). J Med Chem. 2010 Feb 12. PMID:20151677 doi:10.1021/jm901788j

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