3db8: Difference between revisions

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Revision as of 19:31, 7 January 2013

File:3db8.png

Template:STRUCTURE 3db8

Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041

Template:ABSTRACT PUBMED 18790636

About this Structure

3db8 is a 1 chain structure with sequence from Danio rerio. Full crystallographic information is available from OCA.

Reference

  1. Hanan EJ, Fucini RV, Romanowski MJ, Elling RA, Lew W, Purkey HE, VanderPorten EC, Yang W. Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5186-9. Epub 2008 Aug 29. PMID:18790636 doi:10.1016/j.bmcl.2008.08.091

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