2z8c: Difference between revisions

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{{Seed}}
[[Image:2z8c.png|left|200px]]
[[Image:2z8c.png|left|200px]]


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{{STRUCTURE_2z8c|  PDB=2z8c  |  SCENE=  }}  
{{STRUCTURE_2z8c|  PDB=2z8c  |  SCENE=  }}  


===Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid===
===Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid===


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{{ABSTRACT_PUBMED_18767165}}
{{ABSTRACT_PUBMED_18767165}}


==Disease==
==About this Structure==
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Coronary artery disease, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147545 147545]], Diabetes mellitus, noninsulin-dependent OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147545 147545]]
[[2z8c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z8C OCA].  


==About this Structure==
==See Also==
2Z8C is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z8C OCA].
*[[Insulin receptor|Insulin receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:18767165</ref><references group="xtra"/>
<ref group="xtra">PMID:018767165</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Katayama, N.]]
[[Category: Katayama, N.]]
[[Category: Kurihara, H.]]
[[Category: Kurihara, H.]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Carbohydrate metabolism]]
[[Category: Carbohydrate metabolism]]
Line 42: Line 29:
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Polymorphism]]
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Transducer]]
[[Category: Transducer]]
Line 48: Line 34:
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:08:10 2009''