1xoy: Difference between revisions

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==Overview==
==Overview==
The structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of, the C-terminal domain of human thioredoxin-like protein, was determined by, NMR spectroscopy. The structure is dominated by a beta-barrel sandwich. A, two-stranded anti-parallel beta-sheet, which seals off one end of the, beta-barrel, is flanked by two flexible loops rich in acidic amino acids., Although this fold often provides a ligand binding site, the structure did, not reveal an appreciable cavity inside the beta-barrel. The, three-dimensional structure of At3g04780.1-des15 provides an entry point, for understanding its functional role and those of its mammalian homologs.
The structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein, was determined by NMR spectroscopy. The structure is dominated by a beta-barrel sandwich. A two-stranded anti-parallel beta-sheet, which seals off one end of the beta-barrel, is flanked by two flexible loops rich in acidic amino acids. Although this fold often provides a ligand binding site, the structure did not reveal an appreciable cavity inside the beta-barrel. The three-dimensional structure of At3g04780.1-des15 provides an entry point for understanding its functional role and those of its mammalian homologs.


==About this Structure==
==About this Structure==
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[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: CESG, Center.for.Eukaryotic.Structural.Genomics.]]
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
[[Category: Lee, M.S.]]
[[Category: Lee, M S.]]
[[Category: Markley, J.L.]]
[[Category: Markley, J L.]]
[[Category: Robert, C.T.]]
[[Category: Robert, C T.]]
[[Category: Song, J.]]
[[Category: Song, J.]]
[[Category: center for eukaryotic structural genomics]]
[[Category: center for eukaryotic structural genomics]]
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[[Category: unknown function]]
[[Category: unknown function]]


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