3c4f: Difference between revisions

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{{Seed}}
[[Image:3c4f.png|left|200px]]
[[Image:3c4f.png|left|200px]]


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{{STRUCTURE_3c4f|  PDB=3c4f  |  SCENE=  }}  
{{STRUCTURE_3c4f|  PDB=3c4f  |  SCENE=  }}  


===FGFR TYROSINE KINASE DOMAIN IN COMPLEX WITH 3-(3-methoxybenzyl)-7-azaindole===
===FGFR TYROSINE KINASE DOMAIN IN COMPLEX WITH 3-(3-methoxybenzyl)-7-azaindole===


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{{ABSTRACT_PUBMED_18287029}}
{{ABSTRACT_PUBMED_18287029}}


==About this Structure==
==About this Structure==
3C4F is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C4F OCA].  
[[3c4f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C4F OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:18287029</ref><references group="xtra"/>
<ref group="xtra">PMID:018287029</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Wang, W.]]
[[Category: Wang, W.]]
[[Category: Zhang, K Y.J.]]
[[Category: Zhang, K Y.J.]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Chromosomal rearrangement]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Dwarfism]]
[[Category: Dwarfism]]
Line 43: Line 29:
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Receptor tyrosine kinase]]
[[Category: Receptor tyrosine kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
Line 49: Line 34:
[[Category: Tyrosine kinase domain]]
[[Category: Tyrosine kinase domain]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:34:38 2009''

Revision as of 21:25, 7 January 2013

File:3c4f.png

Template:STRUCTURE 3c4f

FGFR TYROSINE KINASE DOMAIN IN COMPLEX WITH 3-(3-methoxybenzyl)-7-azaindole

Template:ABSTRACT PUBMED 18287029

About this Structure

3c4f is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Tsai J, Lee JT, Wang W, Zhang J, Cho H, Mamo S, Bremer R, Gillette S, Kong J, Haass NK, Sproesser K, Li L, Smalley KS, Fong D, Zhu YL, Marimuthu A, Nguyen H, Lam B, Liu J, Cheung I, Rice J, Suzuki Y, Luu C, Settachatgul C, Shellooe R, Cantwell J, Kim SH, Schlessinger J, Zhang KY, West BL, Powell B, Habets G, Zhang C, Ibrahim PN, Hirth P, Artis DR, Herlyn M, Bollag G. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3041-6. Epub 2008 Feb 19. PMID:18287029

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