2vki: Difference between revisions

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{{Seed}}
[[Image:2vki.png|left|200px]]
[[Image:2vki.png|left|200px]]


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{{STRUCTURE_2vki|  PDB=2vki  |  SCENE=  }}  
{{STRUCTURE_2vki|  PDB=2vki  |  SCENE=  }}  


===STRUCTURE OF THE PDK1 PH DOMAIN K465E MUTANT===
===STRUCTURE OF THE PDK1 PH DOMAIN K465E MUTANT===


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{{ABSTRACT_PUBMED_18347057}}
{{ABSTRACT_PUBMED_18347057}}


==About this Structure==
==About this Structure==
2VKI is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKI OCA].  
[[2vki]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKI OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:18347057</ref><references group="xtra"/>
<ref group="xtra">PMID:018347057</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
Line 31: Line 19:
[[Category: Deak, M.]]
[[Category: Deak, M.]]
[[Category: Komander, D.]]
[[Category: Komander, D.]]
[[Category: 3-phosphoinositide]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Cancer]]
[[Category: Cancer]]
[[Category: Cytoplasm]]
[[Category: Diabetes]]
[[Category: Diabetes]]
[[Category: Kinase]]
[[Category: Membrane]]
[[Category: Nucleotide-binding]]
[[Category: Pdk1]]
[[Category: Phosphorylation]]
[[Category: Pi3-kinase]]
[[Category: Pkb]]
[[Category: Pleckstrin homology]]
[[Category: Pleckstrin homology]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:54:36 2009''

Revision as of 21:40, 7 January 2013

File:2vki.png

Template:STRUCTURE 2vki

STRUCTURE OF THE PDK1 PH DOMAIN K465E MUTANT

Template:ABSTRACT PUBMED 18347057

About this Structure

2vki is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bayascas JR, Wullschleger S, Sakamoto K, Garcia-Martinez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR. Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance. Mol Cell Biol. 2008 May;28(10):3258-72. Epub 2008 Mar 17. PMID:18347057 doi:10.1128/MCB.02032-07

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