2xng: Difference between revisions
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[[Image:2xng.png|left|200px]] | [[Image:2xng.png|left|200px]] | ||
{{STRUCTURE_2xng| PDB=2xng | SCENE= }} | {{STRUCTURE_2xng| PDB=2xng | SCENE= }} | ||
===STRUCTURE OF AURORA-A BOUND TO A SELECTIVE IMIDAZOPYRAZINE INHIBITOR=== | ===STRUCTURE OF AURORA-A BOUND TO A SELECTIVE IMIDAZOPYRAZINE INHIBITOR=== | ||
{{ABSTRACT_PUBMED_20833547}} | {{ABSTRACT_PUBMED_20833547}} | ||
==About this Structure== | ==About this Structure== | ||
[[2xng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNG OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020833547</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Ser-thr protein kinase complex]] | [[Category: Ser-thr protein kinase complex]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 22:27, 7 January 2013
STRUCTURE OF AURORA-A BOUND TO A SELECTIVE IMIDAZOPYRAZINE INHIBITOR
Template:ABSTRACT PUBMED 20833547
About this Structure
2xng is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bouloc N, Large JM, Kosmopoulou M, Sun C, Faisal A, Matteucci M, Reynisson J, Brown N, Atrash B, Blagg J, McDonald E, Linardopoulos S, Bayliss R, Bavetsias V. Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells. Bioorg Med Chem Lett. 2010 Oct 15;20(20):5988-93. Epub 2010 Aug 21. PMID:20833547 doi:10.1016/j.bmcl.2010.08.091
