2xck: Difference between revisions

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Revision as of 22:46, 7 January 2013

File:2xck.png

Template:STRUCTURE 2xck

CRYSTAL STRUCTURE OF PDK1 IN COMPLEX WITH A PYRAZOLOQUINAZOLINE INHIBITOR

Template:ABSTRACT PUBMED 20621725

About this Structure

2xck is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Angiolini M, Banfi P, Casale E, Casuscelli F, Fiorelli C, Saccardo MB, Silvagni M, Zuccotto F. Structure-based optimization of potent PDK1 inhibitors. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4095-9. Epub 2010 Jun 8. PMID:20621725 doi:10.1016/j.bmcl.2010.05.070

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