2zi8: Difference between revisions

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Revision as of 23:06, 7 January 2013

File:2zi8.png

Template:STRUCTURE 2zi8

Crystal structure of the HsaC extradiol dioxygenase from M. tuberculosis in complex with 3,4-dihydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione (DHSA)

Template:ABSTRACT PUBMED 19300498

About this Structure

2zi8 is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  1. Yam KC, D'Angelo I, Kalscheuer R, Zhu H, Wang JX, Snieckus V, Ly LH, Converse PJ, Jacobs WR Jr, Strynadka N, Eltis LD. Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis. PLoS Pathog. 2009 Mar;5(3):e1000344. Epub 2009 Mar 20. PMID:19300498 doi:10.1371/journal.ppat.1000344

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