1z27: Difference between revisions

Line 1:

[[Image:1z27.gif|left|200px]]<br /><applet load="1z27" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1z27.gif|left|200px]]<br /><applet load="1z27" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1z27, resolution 2.08Å" />

'''Crystal structure of Native Pvs25, an ookinete protein from Plasmodium vivax.'''<br />

==Overview==

P25 and P28 proteins are essential for Plasmodium parasites to infect, mosquitoes and are leading candidates for a transmission-blocking malaria, vaccine. The Plasmodium vivax P25 is a triangular prism that could tile, the parasite surface. The residues forming the triangle are conserved in, P25 and P28 from all Plasmodium species. A cocrystal structure shows that, a transmission-blocking antibody uses only its heavy chain to bind Pvs25, at a vertex of the triangle.

P25 and P28 proteins are essential for Plasmodium parasites to infect mosquitoes and are leading candidates for a transmission-blocking malaria vaccine. The Plasmodium vivax P25 is a triangular prism that could tile the parasite surface. The residues forming the triangle are conserved in P25 and P28 from all Plasmodium species. A cocrystal structure shows that a transmission-blocking antibody uses only its heavy chain to bind Pvs25 at a vertex of the triangle.

==About this Structure==

1Z27 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1Z27 OCA].

1Z27 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z27 OCA].

==Reference==

Line 13:

[[Category: Plasmodium vivax]]

[[Category: Single protein]]

[[Category: Garboczi, D.N.]]

[[Category: Garboczi, D N.]]

[[Category: Klein, M.M.]]

[[Category: Klein, M M.]]

[[Category: Long, C.A.]]

[[Category: Long, C A.]]

[[Category: Saul, A.J.]]

[[Category: Saul, A J.]]

[[Category: Saxena, A.K.]]

[[Category: Saxena, A K.]]

[[Category: Singh, K.]]

[[Category: Stowers, A.W.]]

[[Category: Stowers, A W.]]

[[Category: Su, H.P.]]

[[Category: Su, H P.]]

[[Category: four egf-like domains]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Sun Nov 25 04~~:42:~~18 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:11:23 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1z27.gif|left|200px]]<br /><applet load="1z27" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1z27.gif|left|200px]]<br /><applet load="1z27" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1z27, resolution 2.08&Aring;" />
 '''Crystal structure of Native Pvs25, an ookinete protein from Plasmodium vivax.'''<br />
 ==Overview==
-P25 and P28 proteins are essential for Plasmodium parasites to infect, mosquitoes and are leading candidates for a transmission-blocking malaria, vaccine. The Plasmodium vivax P25 is a triangular prism that could tile, the parasite surface. The residues forming the triangle are conserved in, P25 and P28 from all Plasmodium species. A cocrystal structure shows that, a transmission-blocking antibody uses only its heavy chain to bind Pvs25, at a vertex of the triangle.
+P25 and P28 proteins are essential for Plasmodium parasites to infect mosquitoes and are leading candidates for a transmission-blocking malaria vaccine. The Plasmodium vivax P25 is a triangular prism that could tile the parasite surface. The residues forming the triangle are conserved in P25 and P28 from all Plasmodium species. A cocrystal structure shows that a transmission-blocking antibody uses only its heavy chain to bind Pvs25 at a vertex of the triangle.
 ==About this Structure==
-Z27 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1Z27 OCA].
+Z27 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z27 OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Plasmodium vivax]]
 [[Category: Single protein]]
-[[Category: Garboczi, D.N.]]
+[[Category: Garboczi, D N.]]
-[[Category: Klein, M.M.]]
+[[Category: Klein, M M.]]
-[[Category: Long, C.A.]]
+[[Category: Long, C A.]]
-[[Category: Saul, A.J.]]
+[[Category: Saul, A J.]]
-[[Category: Saxena, A.K.]]
+[[Category: Saxena, A K.]]
 [[Category: Singh, K.]]
-[[Category: Stowers, A.W.]]
+[[Category: Stowers, A W.]]
-[[Category: Su, H.P.]]
+[[Category: Su, H P.]]
 [[Category: four egf-like domains]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 04:42:18 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:11:23 2008''