2fzp: Difference between revisions

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[[Image:2fzp.png|left|200px]]
[[Image:2fzp.png|left|200px]]


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{{STRUCTURE_2fzp|  PDB=2fzp  |  SCENE=  }}  
{{STRUCTURE_2fzp|  PDB=2fzp  |  SCENE=  }}  


===Crystal structure of the USP8 interaction domain of human NRDP1===
===Crystal structure of the USP8 interaction domain of human NRDP1===


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{{ABSTRACT_PUBMED_17035239}}


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==Reference==
==Reference==
<ref group="xtra">PMID:17035239</ref><ref group="xtra">PMID:15314180</ref><ref group="xtra">PMID:14765125</ref><ref group="xtra">PMID:11867753</ref><ref group="xtra">PMID:11358394</ref><references group="xtra"/>
<ref group="xtra">PMID:017035239</ref><ref group="xtra">PMID:015314180</ref><ref group="xtra">PMID:014765125</ref><ref group="xtra">PMID:011867753</ref><ref group="xtra">PMID:011358394</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C.]]
[[Category: Arrowsmith, C.]]
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[[Category: Xue, S.]]
[[Category: Xue, S.]]
[[Category: E3 ligase]]
[[Category: E3 ligase]]
[[Category: Ligase]]
[[Category: Protein ubiquitination]]
[[Category: Protein ubiquitination]]
[[Category: Sgc]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Structural genomics consortium]]

Revision as of 12:33, 23 January 2013

File:2fzp.png

Template:STRUCTURE 2fzp

Crystal structure of the USP8 interaction domain of human NRDP1

Template:ABSTRACT PUBMED 17035239

About this Structure

2fzp is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Avvakumov GV, Walker JR, Xue S, Finerty PJ Jr, Mackenzie F, Newman EM, Dhe-Paganon S. Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8). J Biol Chem. 2006 Dec 8;281(49):38061-70. Epub 2006 Oct 11. PMID:17035239 doi:10.1074/jbc.M606704200
  2. Wu X, Yen L, Irwin L, Sweeney C, Carraway KL 3rd. Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8. Mol Cell Biol. 2004 Sep;24(17):7748-57. PMID:15314180 doi:10.1128/MCB.24.17.7748-7757.2004
  3. Qiu XB, Markant SL, Yuan J, Goldberg AL. Nrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis. EMBO J. 2004 Feb 25;23(4):800-10. Epub 2004 Feb 12. PMID:14765125 doi:10.1038/sj.emboj.7600075
  4. Diamonti AJ, Guy PM, Ivanof C, Wong K, Sweeney C, Carraway KL 3rd. An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2866-71. Epub 2002 Feb 26. PMID:11867753 doi:10.1073/pnas.052709799
  5. Abdullah JM, Li X, Nachtman RG, Jurecic R. FLRF, a novel evolutionarily conserved RING finger gene, is differentially expressed in mouse fetal and adult hematopoietic stem cells and progenitors. Blood Cells Mol Dis. 2001 Jan-Feb;27(1):320-33. PMID:11358394 doi:10.1006/bcmd.2001.0390

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