Chymotrypsin: Difference between revisions

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=== Native Chymotrypsin ===
=== Native Chymotrypsin ===


[[1yph]] – BtChyA chain A - ''Bos taurus''<br />
[[1yph]] – bChyA chain A - bovine<br />
[[4cha]], [[5cha]] – BtChy<br />
[[4cha]], [[5cha]] – BtChy<br />
[[2jet]] – RnChygen B chain A,B  - ''Rattus norvegicus''<br />
[[2jet]] – rChygen B chain A,B  - rat<br />
[[1kdq]] – RnChyB, chain B (mutant)<br />
[[1kdq]] – rChyB, chain B (mutant)<br />
[[2ea3]] – Chy – ''Cellulomonas bogoriensis''<br />
[[2ea3]] – Chy – ''Cellulomonas bogoriensis''<br />
[[1ab9]], [[8gch]], [[1gct]], [[2gct]], [[3gct]], [[2gch]] - gamma BtChy<br />
[[1ab9]], [[8gch]], [[1gct]], [[2gct]], [[3gct]], [[2gch]] - gamma BtChy<br />


=== Native Chymotrypsinogen ===
=== Native Chymotrypsinogen ===


[[2cga]], [[1chg]] – BtChygen A
[[2cga]], [[1chg]] – bChygen A
 


=== Chymotrypsin + polypeptide inhibitors ===
=== Chymotrypsin + polypeptide inhibitors ===


[[1cbw]], [[1mtn]] - BtChy+BPTI <br />
[[1cbw]], [[1mtn]] - bChy+BPTI <br />
[[1t7c]], [[1t8l]], [[1t8m]], [[1t8n]], [[1t8o]] – BtChyA+P1  BPTI variants<br />
[[1t7c]], [[1t8l]], [[1t8m]], [[1t8n]], [[1t8o]] – bChyA+P1  BPTI variants<br />
[[1oxg]] – BtChyA+autolysis peptide<br />
[[1oxg]] – bChyA+autolysis peptide<br />
[[1p2m]], [[1p2n]], [[1p2o]], [[1p2q]] – BtChyA+ 4 amino acids in S1 pocket<br />
[[1p2m]], [[1p2n]], [[1p2o]], [[1p2q]] – bChyA+ 4 amino acids in S1 pocket<br />
[[1n8o]] – BtChyA+ecotin<br />
[[1n8o]] – bChyA+ecotin<br />
[[1ca0]] – BtChy+APPI <br />
[[1ca0]] – bChy+APPI <br />
[[1acb]] – BtChy+Elgin C <br />
[[1acb]] – bChy+Elgin C <br />
[[2cho]] – BtChy+turkey ovomucoid third domain  
[[2cho]] – bChy+turkey ovomucoid third domain  
 


=== Chymotrypsin + inhibitors ===
=== Chymotrypsin + inhibitors ===


[[3bg4]] – ChyA chain A+guamerin <br />
[[3bg4]] – ChyA chain A+guamerin <br />
[[2p8o]] - BtChyA chain A+benzohydroxamic acid/vanadate <br />
[[2p8o]] - bChyA chain A+benzohydroxamic acid/vanadate <br />
[[1eq9]] – Chy+PMSF – fire ant <br />
[[1eq9]] – Chy+PMSF – fire ant <br />
[[2cha]] –BtChy+p-sulfinotoluene
[[2cha]] – bChy+p-sulfinotoluene
 
 
=== Gamma Chymotrypsin + inhibitors ===
 
[[1gg6]] – gamma BtChy+N-acetyl-phenylalanine trifluoromethyl ketone <br />
[[1ggd]] – gamma BtChy+N-acetyl-phenylalanine trifluoromethyl aldehyde <br />
[[1afq]] - gamma BtChy+synthetic inhibitor<br />
[[3gch]], [[4gch]], [[5gch]] - gamma BtChy+cinnamate <br />
[[6gch]], [[7gch]] - gamma BtChy+trifluoromethy ketone <br />
[[6cha]] – gamma BtChy+phenylethane boronic acid – transition state inhibitor<br />
[[1gmc]], [[1gmd]] – gamma BtChy+hexane – transition state inhibitor<br />
[[2gmt]] - gamma BtChy+N-acetyl-alanyl-phenylalanyl-chloroethyl ketone 1gmh, 1gcd - gamma BtChy+organophosphoryl <br />
[[1gha]], [[1ghb]] - gamma BtChy+ N-acetyl-tryptophan<br />


=== γ-Chymotrypsin + inhibitors ===


[[1gg6]] – γ-bChy+N-acetyl-phenylalanine trifluoromethyl ketone <br />
[[1ggd]] – γ-bChy+N-acetyl-phenylalanine trifluoromethyl aldehyde <br />
[[1afq]] - γ-bChy+synthetic inhibitor<br />
[[3gch]], [[4gch]], [[5gch]] - γ-bChy+cinnamate <br />
[[6gch]], [[7gch]] - γ-bChy+trifluoromethy ketone <br />
[[6cha]] – γ-bChy+phenylethane boronic acid – transition state inhibitor<br />
[[1gmc]], [[1gmd]] – γ-bChy+hexane – transition state inhibitor<br />
[[2gmt]] - γ-bChy+N-acetyl-alanyl-phenylalanyl-chloroethyl ketone<br />
[[1gmh]], [[1gcd]] - γ-bChy+organophosphoryl <br />
[[1gha]], [[1ghb]] - γ-bChy+ N-acetyl-tryptophan<br />
   
   
=== Gamma Chymotrypsin + reaction transition state inhibitors ===
=== γ-Chymotrypsin + reaction transition state inhibitors ===
 
[[6cha]] – gamma BtChy+phenylethane boronic acid <br />
[[1gmc]], [[1gmd]] – gamma BtChy+hexane
 
 
=== Delta Chymotrypsin + inhibitors ===


[[1dlk]] – delta BtChy+peptidyl chloromethyl ketone
[[6cha]] – γ-bChy+phenylethane boronic acid <br />
[[1gmc]], [[1gmd]] – γ-bChy+hexane


=== δ-Chymotrypsin + inhibitors ===


[[1dlk]] – δ-bChy+peptidyl chloromethyl ketone


=== Chymotrypsinogen +  inhibitors ===
=== Chymotrypsinogen +  inhibitors ===


[[1gl0]], [[1gli]] – ChygenA+PMP_D2v – ''Locusta migratoria''<br />
[[1gl0]], [[1gli]] – ChygenA+PMP_D2v – ''Locusta migratoria''<br />
[[1k2i]] -  BtChygen+7-hydroxycoumarin<br />
[[1k2i]] -  bChygen+7-hydroxycoumarin<br />
[[2y6t]] – BtChygenA + ecotin
[[2y6t]] – bChygenA + ecotin


==Further reading==
==Further reading==
Retrieved from "https://proteopedia.org/Chymotrypsin"