2xno: Difference between revisions

Revision as of 13:19, 6 February 2013

2xno is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Solanki S, Innocenti P, Mas-Droux C, Boxall K, Barillari C, van Montfort RL, Aherne GW, Bayliss R, Hoelder S. Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship. J Med Chem. 2011 Mar 24;54(6):1626-39. Epub 2011 Mar 2. PMID:21366329 doi:10.1021/jm1011726

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-[[Image:2xno.jpg|left|200px]]
+[[Image:2xno.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_2xno", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_2xno|  PDB=2xno  |  SCENE=  }}
 ===STRUCTURE OF NEK2 BOUND TO CCT243779===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_21366329}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 21366329 is the PubMed ID number.
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 {{ABSTRACT_PUBMED_21366329}}
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 ==Reference==
-<ref group="xtra">PMID:21366329</ref><references group="xtra"/>
+<ref group="xtra">PMID:021366329</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
 [[Category: Non-specific serine/threonine protein kinase]]
 [[Category: Bayliss, R.]]
 [[Category: Mas-Droux, C.]]
+[[Category: Cell cycle]]
+[[Category: Centrosome]]
+[[Category: Mitosis]]
+[[Category: Transferase]]