3eta: Difference between revisions

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Revision as of 13:30, 6 February 2013

File:3eta.png

Template:STRUCTURE 3eta

Kinase domain of insulin receptor complexed with a pyrrolo pyridine inhibitor

Template:ABSTRACT PUBMED 19394223

About this Structure

3eta is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Patnaik S, Stevens KL, Gerding R, Deanda F, Shotwell JB, Tang J, Hamajima T, Nakamura H, Leesnitzer MA, Hassell AM, Shewchuck LM, Kumar R, Lei H, Chamberlain SD. Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase. Bioorg Med Chem Lett. 2009 Jun 1;19(11):3136-40. Epub 2009 Jan 6. PMID:19394223 doi:10.1016/j.bmcl.2008.12.110

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