3fli: Difference between revisions

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{{Seed}}
[[Image:3fli.png|left|200px]]
[[Image:3fli.jpg|left|200px]]


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{{STRUCTURE_3fli|  PDB=3fli  |  SCENE=  }}  
{{STRUCTURE_3fli|  PDB=3fli  |  SCENE=  }}  


===Discovery of XL335, a Highly Potent, Selective and Orally-Active Agonist of the Farnesoid X Receptor (FXR)===
===Discovery of XL335, a Highly Potent, Selective and Orally-Active Agonist of the Farnesoid X Receptor (FXR)===


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{{ABSTRACT_PUBMED_19159286}}
{{ABSTRACT_PUBMED_19159286}}


==About this Structure==
==About this Structure==
3FLI is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FLI OCA].  
[[3fli]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FLI OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:19159286</ref><references group="xtra"/>
<ref group="xtra">PMID:019159286</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Foster, P G.]]
[[Category: Foster, P G.]]
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[[Category: Activator]]
[[Category: Activator]]
[[Category: Alpha-helical sandwich]]
[[Category: Alpha-helical sandwich]]
[[Category: Alternative splicing]]
[[Category: Bar]]
[[Category: Bar]]
[[Category: Bile acid receptor]]
[[Category: Bile acid receptor]]
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[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
[[Category: Transcriptional regulator]]
[[Category: Transcriptional regulator]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Dec 24 07:31:14 2009''

Revision as of 11:11, 13 February 2013

File:3fli.png

Template:STRUCTURE 3fli

Discovery of XL335, a Highly Potent, Selective and Orally-Active Agonist of the Farnesoid X Receptor (FXR)

Template:ABSTRACT PUBMED 19159286

About this Structure

3fli is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Flatt B, Martin R, Wang TL, Mahaney P, Murphy B, Gu XH, Foster P, Li J, Pircher P, Petrowski M, Schulman I, Westin S, Wrobel J, Yan G, Bischoff E, Daige C, Mohan R. Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR). J Med Chem. 2009 Feb 26;52(4):904-7. PMID:19159286 doi:10.1021/jm8014124

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