3fj6: Difference between revisions
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[[Image:3fj6.png|left|200px]] | |||
[[Image:3fj6. | |||
{{STRUCTURE_3fj6| PDB=3fj6 | SCENE= }} | {{STRUCTURE_3fj6| PDB=3fj6 | SCENE= }} | ||
===Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2=== | ===Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2=== | ||
{{ABSTRACT_PUBMED_19351152}} | {{ABSTRACT_PUBMED_19351152}} | ||
==About this Structure== | ==About this Structure== | ||
[[3fj6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FJ6 OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019351152</ref><references group="xtra"/> | ||
[[Category: Dihydroorotate oxidase]] | [[Category: Dihydroorotate oxidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 34: | Line 22: | ||
[[Category: Mitochondrion inner membrane]] | [[Category: Mitochondrion inner membrane]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Pyrimidine biosynthesis]] | [[Category: Pyrimidine biosynthesis]] | ||
[[Category: Transit peptide]] | [[Category: Transit peptide]] | ||
Revision as of 11:22, 13 February 2013
Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2
Template:ABSTRACT PUBMED 19351152
About this Structure
3fj6 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Davies M, Heikkila T, McConkey GA, Fishwick CW, Parsons MR, Johnson AP. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases. J Med Chem. 2009 May 14;52(9):2683-93. PMID:19351152 doi:10.1021/jm800963t