Thrombin: Difference between revisions

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== 3D Structures of thrombin==
== 3D Structures of thrombin==


''Updated July 2012''
''Updated February 2013''


===Thrombin===
===Thrombin===
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===Thrombin complexes containing hirudin===
===Thrombin complexes containing hirudin===


[[3c27]], [[2zc9]], [[2zda]], [[2zdv]], [[3egk]], [[2r2m]], [[2v3h]], [[2v3o]], [[2pks]], [[3eq0]], [[3dt0]], [[3dux]], [[3da9]], [[3dhk]], [[2znk]], [[2zo3]], [[3d49]], [[2zhe]], [[2zhf]], [[2zhw]], [[2zg0]], [[2zfq]], [[2zfr]], [[2zhq]], [[2zi2]], [[2ziq]], [[2zff]], [[2zfp]], [[2zgb]], [[2zgx]], [[2zf0]], [[3biu]], [[3biv]], [[2uuj]], [[2uuk]], [[2jh0]], [[2jh5]], [[2jh6]], [[2gde]], [[2bxt]], [[2bxu]], [[2bvr]], [[2bvs]], [[2bvx]], [[2bdy]], [[2feq]], [[2c8w]], [[2c8x]], [[2c8y]], [[2c8z]], [[2c90]], [[2c93]], [[2cf8]], [[2cf9]], [[2anm]], [[2w7g]], [[2fes]], [[1ype]], [[1ypg]], [[1ypj]], [[1ypk]], [[1ypl]], [[1ypm]], [[1vzq]], [[1way]], [[1wbg]], [[1riw]], [[1mu6]], [[1mu8]], [[1mue]], [[1nzq]], [[1o0d]], [[1oyt]], [[1o2g]], [[1gj4]], [[1gj5]], [[1kts]], [[1ktt]], [[1ghv]], [[1ghw]], [[1ghx]], [[1ghy]], [[1c5n]], [[1c5o]], [[1c4y]], [[1d3d]], [[1d3p]], [[1d3q]], [[1d3t]], [[1c4u]], [[1c4v]], [[1c1u]], [[1c1v]], [[1c1w]], [[1qj1]], [[1qj6]], [[1qj7]], [[1qhr]], [[1qur]], [[1d4p]], [[1ba8]], [[1bb0]], [[1ca8]], [[1awf]], [[1awh]], [[1bcu]], [[1a61]], [[1a3b]], [[1a3e]], [[1a46]], [[1a5g]], [[1b5g]], [[1tbz]], [[1a4w]], [[1ay6]], [[1ae8]], [[1afe]], [[1ad8]], [[1ai8]], [[1aix]], [[1bmm]], [[1bmn]], [[1lhc]], [[1lhd]], [[1lhe]], [[1lhf]], [[1lhg]], [[1uma]], [[1aht]], [[1fpc]], [[1w7g]], [[3ldx]], [[3p17]], [[3qto]], [[3qtv]], [[3qwc]], [[3qxs]], [[3rlw]], [[3rly]], [[3rm0]], [[3rm2]], [[3rml]], [[3rmm]], [[3rmn]], [[3rmo]] - hThr HC + LC + hirudin peptide + inhibitor<br />
[[3c27]], [[2zc9]], [[2zda]], [[2zdv]], [[3egk]], [[2r2m]], [[2v3h]], [[2v3o]], [[2pks]], [[3eq0]], [[3dt0]], [[3dux]], [[3da9]], [[3dhk]], [[2znk]], [[2zo3]], [[3d49]], [[2zhe]], [[2zhf]], [[2zhw]], [[2zg0]], [[2zfq]], [[2zfr]], [[2zhq]], [[2zi2]], [[2ziq]], [[2zff]], [[2zfp]], [[2zgb]], [[2zgx]], [[2zf0]], [[3biu]], [[3biv]], [[2uuj]], [[2uuk]], [[2jh0]], [[2jh5]], [[2jh6]], [[2gde]], [[2bxt]], [[2bxu]], [[2bvr]], [[2bvs]], [[2bvx]], [[2bdy]], [[2feq]], [[2c8w]], [[2c8x]], [[2c8y]], [[2c8z]], [[2c90]], [[2c93]], [[2cf8]], [[2cf9]], [[2anm]], [[2w7g]], [[2fes]], [[1ype]], [[1ypg]], [[1ypj]], [[1ypk]], [[1ypl]], [[1ypm]], [[1vzq]], [[1way]], [[1wbg]], [[1riw]], [[1mu6]], [[1mu8]], [[1mue]], [[1nzq]], [[1o0d]], [[1oyt]], [[1o2g]], [[1gj4]], [[1gj5]], [[1kts]], [[1ktt]], [[1ghv]], [[1ghw]], [[1ghx]], [[1ghy]], [[1c5n]], [[1c5o]], [[1c4y]], [[1d3d]], [[1d3p]], [[1d3q]], [[1d3t]], [[1c4u]], [[1c4v]], [[1c1u]], [[1c1v]], [[1c1w]], [[1qj1]], [[1qj6]], [[1qj7]], [[1qhr]], [[1qur]], [[1d4p]], [[1ba8]], [[1bb0]], [[1ca8]], [[1awf]], [[1awh]], [[1bcu]], [[1a61]], [[1a3b]], [[1a3e]], [[1a46]], [[1a5g]], [[1b5g]], [[1tbz]], [[1a4w]], [[1ay6]], [[1ae8]], [[1afe]], [[1ad8]], [[1ai8]], [[1aix]], [[1bmm]], [[1bmn]], [[1lhc]], [[1lhd]], [[1lhe]], [[1lhf]], [[1lhg]], [[1uma]], [[1aht]], [[1fpc]], [[1w7g]], [[3ldx]], [[3p17]], [[3qto]], [[3qtv]], [[3qwc]], [[3qxs]], [[3rlw]], [[3rly]], [[3rm0]], [[3rm2]], [[3rml]], [[3rmm]], [[3rmn]], [[3rmo]], [[3t5f]], [[3sv2]], [[3si3]], [[3si4]], [[3sha]], [[3shc]], [[3u98]], [[3u9a]], [[3uwj]], [[4e7r]] - hThr HC + LC + hirudin peptide + inhibitor<br />
[[1zgi]], [[1zgv]], [[1zrb]], [[1z71]], [[1xm1]], [[1sl3]], [[1ta2]], [[1ta6]], [[1nm6]], [[1nt1]], [[1doj]], [[1d9i]], [[1d6w]], [[1qbv]], [[1tmu]], [[1dwb]], [[1dwc]], [[1dwd]], [[1dwe]] - hThr HC + hirudin peptide + inhibitor<br />
[[1zgi]], [[1zgv]], [[1zrb]], [[1z71]], [[1xm1]], [[1sl3]], [[1ta2]], [[1ta6]], [[1nm6]], [[1nt1]], [[1doj]], [[1d9i]], [[1d6w]], [[1qbv]], [[1tmu]], [[1dwb]], [[1dwc]], [[1dwd]], [[1dwe]] - hThr HC + hirudin peptide + inhibitor<br />
[[1ny2]], [[8kme]], [[7kme]], [[1a2c]], [[1tom]], [[1hdt]], [[1tmt]], [[1tmb]] - hThr HC + LC + hirudin peptide + peptide inhibitor<br />
[[1ny2]], [[8kme]], [[7kme]], [[1a2c]], [[1tom]], [[1hdt]], [[1tmt]], [[1tmb]], [[3u8o]], [[3u8r]] - hThr HC + LC + hirudin peptide + peptide inhibitor<br />
[[3hat]] - hThr HC + LC + hirudin peptide + fibrinogen peptide<br />
[[3hat]] - hThr HC + LC + hirudin peptide + fibrinogen peptide<br />
[[2uuf]], [[2pw8]], [[1no9]], [[1c5l]], [[1vr1]], [[4thn]], [[5gds]], [[1hxf]], [[1hxe]], [[1abi]], [[1hgt]], [[1ihs]], [[1iht]], [[1thr]], [[1ths]], [[2hgt]] - hThr HC + LC + hirudin peptide<br />
[[2uuf]], [[2pw8]], [[1no9]], [[1c5l]], [[1vr1]], [[4thn]], [[5gds]], [[1hxf]], [[1hxe]], [[1abi]], [[1hgt]], [[1ihs]], [[1iht]], [[1thr]], [[1ths]], [[2hgt]], [[3utu]], [[4ayv]], [[4ayy]], [[4az2]] - hThr HC + LC + hirudin peptide<br />
[[1vit]] - bThr HC + LC + hirudin peptide<br />
[[1vit]] - bThr HC + LC + hirudin peptide<br />


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[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />
[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />
[[3lu9]], [[3bef]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />
[[3lu9]], [[3bef]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />
[[1sr5]] - hPThr HC + LC + antithrombin III<br />
[[3k65]] - hPThr HC residues 315-622 (mutant) + LC residues 199-314<br />
[[3k65]] - hPThr HC residues 315-622 (mutant) + LC residues 199-314<br />
[[3f68]] - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide<br />
[[3f68]] - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide<br />
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