4iw5: Difference between revisions
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[[Image:4iw5.jpg|left|200px]] | |||
{{STRUCTURE_4iw5| PDB=4iw5 | SCENE= }} | |||
===Thymidylate synthase ternary complex with dUMP and CB3717=== | |||
{{ABSTRACT_PUBMED_16768437}} | |||
==About this Structure== | |||
[[4iw5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2g8o 2g8o]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IW5 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:016768437</ref><references group="xtra"/> | |||
[[Category: Escherichia coli k-12]] | |||
[[Category: Thymidylate synthase]] | |||
[[Category: Finer-Moore, J.]] | |||
[[Category: Lee, T T.]] | |||
[[Category: Newby, Z.]] | |||
[[Category: Stroud, R M.]] | |||
[[Category: Alpha/beta protein]] | |||
[[Category: Antifolate]] | |||
[[Category: Methylenetetrahydrofolate]] | |||
[[Category: Methyltransferase]] | |||
[[Category: Transferase]] | |||
Revision as of 13:47, 20 February 2013
Thymidylate synthase ternary complex with dUMP and CB3717
Template:ABSTRACT PUBMED 16768437
About this Structure
4iw5 is a 2 chain structure with sequence from Escherichia coli k-12. This structure supersedes the now removed PDB entry 2g8o. Full crystallographic information is available from OCA.
Reference
- Newby Z, Lee TT, Morse RJ, Liu Y, Liu L, Venkatraman P, Santi DV, Finer-Moore JS, Stroud RM. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261. Biochemistry. 2006 Jun 20;45(24):7415-28. PMID:16768437 doi:10.1021/bi060152s