3kle: Difference between revisions
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{{STRUCTURE_3kle| PDB=3kle | SCENE= }} | {{STRUCTURE_3kle| PDB=3kle | SCENE= }} | ||
===Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA=== | ===Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA=== | ||
{{ABSTRACT_PUBMED_20852643}} | {{ABSTRACT_PUBMED_20852643}} | ||
Revision as of 09:07, 11 March 2013
Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA
Template:ABSTRACT PUBMED 20852643
About this Structure
3kle is a 16 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Human immunodeficiency virus 1
- Arnold, E.
- Das, K.
- Sarafianos, S G.
- Tu, X.
- Aid
- Azt
- Azt adenosine dinucleoside tetraphosphate
- Azt resistance mechanism
- Aztp4a
- Aztppppa
- Dna polymerase
- Dna-directed dna polymerase
- Endonuclease
- Hiv
- Hiv-1
- Hydrolase
- Magnesium
- Metal-binding
- Multifunctional enzyme
- Myristate
- Nrti
- Nrti resistance
- Nuclease
- Nucleoside inhibitor
- Nucleotide excision
- P51/p66
- Resistance mutation
- Reverse transcriptase
- Rna-directed dna polymerase
- Rt
- Thymidine analog mutation
- Transferase
- Transferase-dna complex
