2bkt: Difference between revisions

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==Overview==
==Overview==
We have found that both enantiomeric configurations of the, 6-alkoxymethyl-1-aryl-2-piperazinone scaffold display equipotent renin, inhibition activity and similar SAR patterns. This enantiomeric, flexibility is in contrast to a previously reported, 3-alkoxymethyl-4-arylpiperidine scaffold.
We have found that both enantiomeric configurations of the 6-alkoxymethyl-1-aryl-2-piperazinone scaffold display equipotent renin inhibition activity and similar SAR patterns. This enantiomeric flexibility is in contrast to a previously reported 3-alkoxymethyl-4-arylpiperidine scaffold.


==Disease==
==Disease==
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[[Category: Renin]]
[[Category: Renin]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Bryant, J.W.]]
[[Category: Bryant, J W.]]
[[Category: Clay, E.H.]]
[[Category: Clay, E H.]]
[[Category: Edmunds, J.J.]]
[[Category: Edmunds, J J.]]
[[Category: Holsworth, D.D.]]
[[Category: Holsworth, D D.]]
[[Category: Jalaie, M.]]
[[Category: Jalaie, M.]]
[[Category: Powell, N.A.]]
[[Category: Powell, N A.]]
[[Category: Ryan, J.M.]]
[[Category: Ryan, J M.]]
[[Category: Zhang, E.]]
[[Category: Zhang, E.]]
[[Category: RPF]]
[[Category: RPF]]
Line 30: Line 30:
[[Category: renin]]
[[Category: renin]]


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