2btf: Difference between revisions

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[[Image:2btf.gif|left|200px]]<br /><applet load="2btf" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:2btf.gif|left|200px]]<br /><applet load="2btf" size="350" color="white" frame="true" align="right" spinBox="true"

caption="2btf, resolution 2.55Å" />

'''THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN'''<br />

==Overview==

The three-dimensional structure of bovine profilin-beta-actin has been, solved to 2.55 A resolution by X-ray crystallography. There are several, significant local changes in the structure of beta-actin compared with, alpha-actin as well as an overall 5 degrees rotation between its two major, domains. Actin molecules in the crystal are organized into ribbons through, intermolecular contacts like those found in oligomeric protein assemblies., Profilin forms two extensive contacts with the actin ribbon, one of which, appears to correspond to the solution contact in vitro.

The three-dimensional structure of bovine profilin-beta-actin has been solved to 2.55 A resolution by X-ray crystallography. There are several significant local changes in the structure of beta-actin compared with alpha-actin as well as an overall 5 degrees rotation between its two major domains. Actin molecules in the crystal are organized into ribbons through intermolecular contacts like those found in oligomeric protein assemblies. Profilin forms two extensive contacts with the actin ribbon, one of which appears to correspond to the solution contact in vitro.

==About this Structure==

2BTF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with SR, ACE, CH3 and ATP as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=2BTF OCA].

2BTF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=SR:'>SR</scene>, <scene name='pdbligand=ACE:'>ACE</scene>, <scene name='pdbligand=CH3:'>CH3</scene> and <scene name='pdbligand=ATP:'>ATP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BTF OCA].

==Reference==

Line 13:

[[Category: Bos taurus]]

[[Category: Protein complex]]

[[Category: Goonesekere, N.C.W.]]

[[Category: Goonesekere, N C.W.]]

[[Category: Myslik, J.C.]]

[[Category: Myslik, J C.]]

[[Category: Rozycki, M.D.]]

[[Category: Rozycki, M D.]]

[[Category: Schutt, C.E.]]

[[Category: Schutt, C E.]]

[[Category: ACE]]

[[Category: ATP]]

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[[Category: acetylation and actin-binding]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Wed Nov~~ 21 08:54:~~34 2007~~''

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@@ Line 1: / Line 1: @@
-[[Image:2btf.gif|left|200px]]<br /><applet load="2btf" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:2btf.gif|left|200px]]<br /><applet load="2btf" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="2btf, resolution 2.55&Aring;" />
 '''THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN'''<br />
 ==Overview==
-The three-dimensional structure of bovine profilin-beta-actin has been, solved to 2.55 A resolution by X-ray crystallography. There are several, significant local changes in the structure of beta-actin compared with, alpha-actin as well as an overall 5 degrees rotation between its two major, domains. Actin molecules in the crystal are organized into ribbons through, intermolecular contacts like those found in oligomeric protein assemblies., Profilin forms two extensive contacts with the actin ribbon, one of which, appears to correspond to the solution contact in vitro.
+The three-dimensional structure of bovine profilin-beta-actin has been solved to 2.55 A resolution by X-ray crystallography. There are several significant local changes in the structure of beta-actin compared with alpha-actin as well as an overall 5 degrees rotation between its two major domains. Actin molecules in the crystal are organized into ribbons through intermolecular contacts like those found in oligomeric protein assemblies. Profilin forms two extensive contacts with the actin ribbon, one of which appears to correspond to the solution contact in vitro.
 ==About this Structure==
-BTF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with SR, ACE, CH3 and ATP as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BTF OCA].
+BTF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=SR:'>SR</scene>, <scene name='pdbligand=ACE:'>ACE</scene>, <scene name='pdbligand=CH3:'>CH3</scene> and <scene name='pdbligand=ATP:'>ATP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BTF OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Bos taurus]]
 [[Category: Protein complex]]
-[[Category: Goonesekere, N.C.W.]]
+[[Category: Goonesekere, N C.W.]]
-[[Category: Myslik, J.C.]]
+[[Category: Myslik, J C.]]
-[[Category: Rozycki, M.D.]]
+[[Category: Rozycki, M D.]]
-[[Category: Schutt, C.E.]]
+[[Category: Schutt, C E.]]
 [[Category: ACE]]
 [[Category: ATP]]
@@ Line 23: / Line 23: @@
 [[Category: acetylation and actin-binding]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 08:54:34 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:41:26 2008''