3img: Difference between revisions
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{{STRUCTURE_3img| PDB=3img | SCENE= }} | {{STRUCTURE_3img| PDB=3img | SCENE= }} | ||
===Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.8 Ang resolution in a ternary complex with fragment compounds 5-methoxyindole and 1-benzofuran-2-carboxylic acid=== | ===Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.8 Ang resolution in a ternary complex with fragment compounds 5-methoxyindole and 1-benzofuran-2-carboxylic acid=== | ||
==About this Structure== | ==About this Structure== | ||
[[3img]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMG OCA]. | [[3img]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMG OCA]. | ||
==See Also== | |||
*[[Pantothenate synthetase|Pantothenate synthetase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:019780086</ref><references group="xtra"/> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Pantoate--beta-alanine ligase]] | [[Category: Pantoate--beta-alanine ligase]] | ||
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[[Category: Silvestre, H L.]] | [[Category: Silvestre, H L.]] | ||
[[Category: Wen, S.]] | [[Category: Wen, S.]] | ||
[[Category: Atp-binding]] | |||
[[Category: Drug design]] | |||
[[Category: Enzyme]] | |||
[[Category: Fragment-based]] | |||
[[Category: Ligase]] | |||
[[Category: Magnesium]] | |||
[[Category: Metal-binding]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Nucleotide-binding]] | |||
[[Category: Pantothenate biosynthesis]] | |||
Revision as of 11:03, 13 March 2013
Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.8 Ang resolution in a ternary complex with fragment compounds 5-methoxyindole and 1-benzofuran-2-carboxylic acid
About this Structure
3img is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Hung AW, Silvestre HL, Wen S, Ciulli A, Blundell TL, Abell C. Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase. Angew Chem Int Ed Engl. 2009;48(45):8452-6. PMID:19780086 doi:10.1002/anie.200903821
