2bur: Difference between revisions

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==Overview==
==Overview==
The catechol dioxygenases allow a wide variety of bacteria to use aromatic, compounds as carbon sources by catalyzing the key ring-opening step. These, enzymes use specifically either catechol or protocatechuate, (2,3-dihydroxybenozate) as their substrates; they use a bare metal ion as, the sole cofactor. To learn how this family of metalloenzymes functions, a, structural analysis of designed and selected mutants of these enzymes has, been undertaken. Here we review the results of this analysis on the, nonheme ferric iron intradiol dioxygenase protocatechuate 3,4-dioxygenase.
The catechol dioxygenases allow a wide variety of bacteria to use aromatic compounds as carbon sources by catalyzing the key ring-opening step. These enzymes use specifically either catechol or protocatechuate (2,3-dihydroxybenozate) as their substrates; they use a bare metal ion as the sole cofactor. To learn how this family of metalloenzymes functions, a structural analysis of designed and selected mutants of these enzymes has been undertaken. Here we review the results of this analysis on the nonheme ferric iron intradiol dioxygenase protocatechuate 3,4-dioxygenase.


==About this Structure==
==About this Structure==
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[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Protocatechuate 3,4-dioxygenase]]
[[Category: Protocatechuate 3,4-dioxygenase]]
[[Category: Argenio, D.A.D.]]
[[Category: Argenio, D A.D.]]
[[Category: Lipscomb, J.D.]]
[[Category: Lipscomb, J D.]]
[[Category: Ohlendorf, D.H.]]
[[Category: Ohlendorf, D H.]]
[[Category: Ornston, L.N.]]
[[Category: Ornston, L N.]]
[[Category: Valley, M.P.]]
[[Category: Valley, M P.]]
[[Category: Vetting, M.W.]]
[[Category: Vetting, M W.]]
[[Category: FE]]
[[Category: FE]]
[[Category: PHB]]
[[Category: PHB]]
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[[Category: non-heme iron]]
[[Category: non-heme iron]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:41:51 2008''