Prion: Difference between revisions

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'''Prion''' (PrP) is a protein which becomes infectious upon undergoing conformation change to an amyloid form, which is self-propagating and becomes resistant to protease degradation. The fungus ''Podospora anserine'' has a prion-like protein HET-S which undergoes a conformation change to amyloid form which prevents its colony from merging with non-compatible colonies. Yeast prion proteins are Sup35 and Ure2. The images at the left and at the right correspond to one representative prion, ''i.e.'' the crystal structure of human prion ([[3haf]]). For more details see [[Prion protein]]. Click here to see <scene name='Prion/Cv/2'>example of prion unfolding</scene> (morph was taken from [http://molmovdb.org/cgi-bin/movie.cgi Gallery of Morphs] of the [http://molmovdb.org Yale Morph Server]).

'''Prion''' (PrP) is a protein which becomes infectious upon undergoing conformation change to an amyloid form, which is self-propagating and becomes resistant to protease degradation. The fungus ''Podospora anserine'' has a prion-like protein HET-S which undergoes a conformation change to amyloid form which prevents its colony from merging with non-compatible colonies. Yeast prion proteins are Sup35 and Ure2. The images at the left and at the right correspond to one representative prion, ''i.e.'' the crystal structure of human prion ([[3haf]]). For more details see [[Prion protein]] and [[Human Prion Protein Dimer]]. Click here to see <scene name='Prion/Cv/2'>example of prion unfolding</scene> (morph was taken from [http://molmovdb.org/cgi-bin/movie.cgi Gallery of Morphs] of the [http://molmovdb.org Yale Morph Server]).

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Revision as of 10:53, 17 March 2013 view source Michal Harel (talk \| contribs) 32,831 edits No edit summary ← Older edit		Revision as of 10:57, 17 March 2013 view source Michal Harel (talk \| contribs) 32,831 edits No edit summary Newer edit →
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	'''Prion''' (PrP) is a protein which becomes infectious upon undergoing conformation change to an amyloid form, which is self-propagating and becomes resistant to protease degradation. The fungus ''Podospora anserine'' has a prion-like protein HET-S which undergoes a conformation change to amyloid form which prevents its colony from merging with non-compatible colonies. Yeast prion proteins are Sup35 and Ure2. The images at the left and at the right correspond to one representative prion, ''i.e.'' the crystal structure of human prion ([[3haf]]). For more details see [[Prion protein]]. Click here to see <scene name='Prion/Cv/2'>example of prion unfolding</scene> (morph was taken from [http://molmovdb.org/cgi-bin/movie.cgi Gallery of Morphs] of the [http://molmovdb.org Yale Morph Server]).		'''Prion''' (PrP) is a protein which becomes infectious upon undergoing conformation change to an amyloid form, which is self-propagating and becomes resistant to protease degradation. The fungus ''Podospora anserine'' has a prion-like protein HET-S which undergoes a conformation change to amyloid form which prevents its colony from merging with non-compatible colonies. Yeast prion proteins are Sup35 and Ure2. The images at the left and at the right correspond to one representative prion, ''i.e.'' the crystal structure of human prion ([[3haf]]). For more details see [[Prion protein]] and [[Human Prion Protein Dimer]]. Click here to see <scene name='Prion/Cv/2'>example of prion unfolding</scene> (morph was taken from [http://molmovdb.org/cgi-bin/movie.cgi Gallery of Morphs] of the [http://molmovdb.org Yale Morph Server]).

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