Helicase: Difference between revisions
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==The Superfamily 1 (SF1)== | ==The Superfamily 1 (SF1)== | ||
PcrA share structural domains with the Rec helicases, like UvrD and RepD from E. coli, Superfamily 1 (SF1) helicases are probably the best characterized class, certainly from a structural perspective. All members characterized to date are bona fide helicases and α enzymes. Indeed, from their mode of translocation via the bases it is difficult to envisage how they could translocate along a duplex. However, they can have either A or B directional polarity.<applet load='2is1' size='300' frame='true' align='left' scene=''|UvrD Structure /><applet load='1uaa' size='300' frame='true' align='center' scene='' |RecD Structure /> | PcrA share structural domains with the Rec helicases, like UvrD and RepD from E. coli, Superfamily 1 (SF1) helicases are probably the best characterized class, certainly from a structural perspective. All members characterized to date are bona fide helicases and α enzymes. Indeed, from their mode of translocation via the bases it is difficult to envisage how they could translocate along a duplex. However, they can have either A or B directional polarity.<applet load='2is1' size='300' frame='true' align='left' caption='[[2is1]]' scene=''|UvrD Structure /><applet load='1uaa' size='300' frame='true' align='center' caption='[[1uaa]]' scene='' |RecD Structure /> | ||
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