2c0w: Difference between revisions

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[[Image:2c0w.gif|left|200px]]<br /><applet load="2c0w" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:2c0w.gif|left|200px]]<br /><applet load="2c0w" size="350" color="white" frame="true" align="right" spinBox="true"

caption="2c0w, resolution 3.2Å" />

'''MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION'''<br />

==Overview==

Filamentous bacteriophage (Inovirus) is a simple and well-characterized, model system. The phage particle, or virion, is about 60 angstroms in, diameter and several thousand angstrom units long. The virions are, assembled at the bacterial membrane as they extrude out of the host, without killing it, an example of specific transport of nucleoprotein, assemblages across membranes. The Ff group (fd, f1 and M13) has been, especially widely studied. Models of virion assembly have been proposed, based on a molecular model of the fd virion derived by X-ray fibre, diffraction. A somewhat different model of the fd virion using solid-state, NMR data has been proposed, not consistent with these models of assembly, nor with the X-ray diffraction data. Here we show that reinterpreted NMR, data are also consistent with the model derived from X-ray fibre, diffraction studies, and discuss models of virion assembly.

Filamentous bacteriophage (Inovirus) is a simple and well-characterized model system. The phage particle, or virion, is about 60 angstroms in diameter and several thousand angstrom units long. The virions are assembled at the bacterial membrane as they extrude out of the host without killing it, an example of specific transport of nucleoprotein assemblages across membranes. The Ff group (fd, f1 and M13) has been especially widely studied. Models of virion assembly have been proposed based on a molecular model of the fd virion derived by X-ray fibre diffraction. A somewhat different model of the fd virion using solid-state NMR data has been proposed, not consistent with these models of assembly nor with the X-ray diffraction data. Here we show that reinterpreted NMR data are also consistent with the model derived from X-ray fibre diffraction studies, and discuss models of virion assembly.

==About this Structure==

2C0W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Phage_phi3t Phage phi3t]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=2C0W OCA].

2C0W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Phage_phi3t Phage phi3t]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0W OCA].

==Reference==

Line 13:

[[Category: Phage phi3t]]

[[Category: Single protein]]

[[Category: Marvin, D.A.]]

[[Category: Marvin, D A.]]

[[Category: Scott, W.R.P.]]

[[Category: Scott, W R.P.]]

[[Category: Straus, S.K.]]

[[Category: Straus, S K.]]

[[Category: Symmons, M.F.]]

[[Category: Symmons, M F.]]

[[Category: Welsh, L.C.]]

[[Category: Welsh, L C.]]

[[Category: alpha-helix]]

[[Category: capsid protein]]

Line 26:

[[Category: transmembrane]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Wed Nov~~ 21 08:58:~~52 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:43:53 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2c0w.gif|left|200px]]<br /><applet load="2c0w" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:2c0w.gif|left|200px]]<br /><applet load="2c0w" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="2c0w, resolution 3.2&Aring;" />
 '''MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION'''<br />
 ==Overview==
-Filamentous bacteriophage (Inovirus) is a simple and well-characterized, model system. The phage particle, or virion, is about 60 angstroms in, diameter and several thousand angstrom units long. The virions are, assembled at the bacterial membrane as they extrude out of the host, without killing it, an example of specific transport of nucleoprotein, assemblages across membranes. The Ff group (fd, f1 and M13) has been, especially widely studied. Models of virion assembly have been proposed, based on a molecular model of the fd virion derived by X-ray fibre, diffraction. A somewhat different model of the fd virion using solid-state, NMR data has been proposed, not consistent with these models of assembly, nor with the X-ray diffraction data. Here we show that reinterpreted NMR, data are also consistent with the model derived from X-ray fibre, diffraction studies, and discuss models of virion assembly.
+Filamentous bacteriophage (Inovirus) is a simple and well-characterized model system. The phage particle, or virion, is about 60 angstroms in diameter and several thousand angstrom units long. The virions are assembled at the bacterial membrane as they extrude out of the host without killing it, an example of specific transport of nucleoprotein assemblages across membranes. The Ff group (fd, f1 and M13) has been especially widely studied. Models of virion assembly have been proposed based on a molecular model of the fd virion derived by X-ray fibre diffraction. A somewhat different model of the fd virion using solid-state NMR data has been proposed, not consistent with these models of assembly nor with the X-ray diffraction data. Here we show that reinterpreted NMR data are also consistent with the model derived from X-ray fibre diffraction studies, and discuss models of virion assembly.
 ==About this Structure==
-C0W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Phage_phi3t Phage phi3t]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C0W OCA].
+C0W is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Phage_phi3t Phage phi3t]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C0W OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Phage phi3t]]
 [[Category: Single protein]]
-[[Category: Marvin, D.A.]]
+[[Category: Marvin, D A.]]
-[[Category: Scott, W.R.P.]]
+[[Category: Scott, W R.P.]]
-[[Category: Straus, S.K.]]
+[[Category: Straus, S K.]]
-[[Category: Symmons, M.F.]]
+[[Category: Symmons, M F.]]
-[[Category: Welsh, L.C.]]
+[[Category: Welsh, L C.]]
 [[Category: alpha-helix]]
 [[Category: capsid protein]]
@@ Line 26: / Line 26: @@
 [[Category: transmembrane]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 08:58:52 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:43:53 2008''