3up0: Difference between revisions

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[[Image:3up0.png|left|200px]]
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{{STRUCTURE_3up0|  PDB=3up0  |  SCENE=  }}  
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===Nuclear receptor DAF-12 from hookworm Ancylostoma ceylanicum in complex with (25S)-delta7-dafachronic acid===
===Nuclear receptor DAF-12 from hookworm Ancylostoma ceylanicum in complex with (25S)-delta7-dafachronic acid===
{{ABSTRACT_PUBMED_22170062}}


==Disease==
[[http://www.uniprot.org/uniprot/NCOA2_HUMAN NCOA2_HUMAN]] Note=Chromosomal aberrations involving NCOA2 may be a cause of acute myeloid leukemias. Inversion inv(8)(p11;q13) generates the KAT6A-NCOA2 oncogene, which consists of the N-terminal part of KAT6A and the C-terminal part of NCOA2/TIF2. KAT6A-NCOA2 binds to CREBBP and disrupts its function in transcription activation.


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==Function==
The line below this paragraph, {{ABSTRACT_PUBMED_22170062}}, adds the Publication Abstract to the page
[[http://www.uniprot.org/uniprot/NCOA2_HUMAN NCOA2_HUMAN]] Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues.<ref>PMID:9430642</ref>  
(as it appears on PubMed at http://www.pubmed.gov), where 22170062 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22170062}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:022170062</ref><references group="xtra"/>
<ref group="xtra">PMID:022170062</ref><references group="xtra"/><references/>
[[Category: Ancylostoma ceylanicum]]
[[Category: Ancylostoma ceylanicum]]
[[Category: Gelmedin, V.]]
[[Category: Gelmedin, V.]]