2yqk: Difference between revisions
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{{STRUCTURE_2yqk| PDB=2yqk | SCENE= }} | {{STRUCTURE_2yqk| PDB=2yqk | SCENE= }} | ||
===Solution structure of the SANT domain in Arginine-glutamic acid dipeptide (RE) repeats=== | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/RERE_HUMAN RERE_HUMAN]] Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line NGP. Translocation t(1;15)(p36.2;q24). | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RERE_HUMAN RERE_HUMAN]] Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.<ref>PMID:11331249</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[2yqk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQK OCA]. | [[2yqk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQK OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: He, F.]] | [[Category: He, F.]] | ||
