1nq7: Difference between revisions
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{{STRUCTURE_1nq7| PDB=1nq7 | SCENE= }} | {{STRUCTURE_1nq7| PDB=1nq7 | SCENE= }} | ||
===Characterization of ligands for the orphan nuclear receptor RORbeta=== | ===Characterization of ligands for the orphan nuclear receptor RORbeta=== | ||
{{ABSTRACT_PUBMED_12958591}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RORB_RAT RORB_RAT]] Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:012958591</ref><references group="xtra"/> | <ref group="xtra">PMID:012958591</ref><references group="xtra"/><references/> | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Dorsselaer, A Van.]] | [[Category: Dorsselaer, A Van.]] | ||
Revision as of 12:03, 24 March 2013
Characterization of ligands for the orphan nuclear receptor RORbeta
Template:ABSTRACT PUBMED 12958591
Function
[RORB_RAT] Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter.
About this Structure
1nq7 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Stehlin-Gaon C, Willmann D, Zeyer D, Sanglier S, Van Dorsselaer A, Renaud JP, Moras D, Schule R. All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta. Nat Struct Biol. 2003 Oct;10(10):820-5. Epub 2003 Sep 7. PMID:12958591 doi:https://dx.doi.org/10.1038/nsb979
