1kvk: Difference between revisions
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{{STRUCTURE_1kvk| PDB=1kvk | SCENE= }} | {{STRUCTURE_1kvk| PDB=1kvk | SCENE= }} | ||
===The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease=== | |||
{{ABSTRACT_PUBMED_11877411}} | |||
== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/KIME_RAT KIME_RAT]] Note=Mutation in the mevalonate kinase gene causes mevalonicaciduria. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KIME_RAT KIME_RAT]] May be a regulatory site in cholesterol biosynthetic pathway. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:011877411</ref><references group="xtra"/> | <ref group="xtra">PMID:011877411</ref><references group="xtra"/><references/> | ||
[[Category: Mevalonate kinase]] | [[Category: Mevalonate kinase]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
Revision as of 17:03, 24 March 2013
The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
Template:ABSTRACT PUBMED 11877411
Disease
[KIME_RAT] Note=Mutation in the mevalonate kinase gene causes mevalonicaciduria.
Function
[KIME_RAT] May be a regulatory site in cholesterol biosynthetic pathway.
About this Structure
1kvk is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Fu Z, Wang M, Potter D, Miziorko HM, Kim JJ. The structure of a binary complex between a mammalian mevalonate kinase and ATP: insights into the reaction mechanism and human inherited disease. J Biol Chem. 2002 May 17;277(20):18134-42. Epub 2002 Feb 27. PMID:11877411 doi:10.1074/jbc.M200912200
