3kc0: Difference between revisions
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{{STRUCTURE_3kc0| PDB=3kc0 | SCENE= }} | {{STRUCTURE_3kc0| PDB=3kc0 | SCENE= }} | ||
===Crystal structure of human liver FBPase in complex with tricyclic inhibitor 10b=== | ===Crystal structure of human liver FBPase in complex with tricyclic inhibitor 10b=== | ||
{{ABSTRACT_PUBMED_20045638}} | |||
==Disease== | |||
[[http://www.uniprot.org/uniprot/F16P1_HUMAN F16P1_HUMAN]] Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:[http://omim.org/entry/229700 229700]]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.<ref>PMID:9382095</ref><ref>PMID:12126934</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:020045638</ref><references group="xtra"/> | <ref group="xtra">PMID:020045638</ref><references group="xtra"/><references/> | ||
[[Category: Fructose-bisphosphatase]] | [[Category: Fructose-bisphosphatase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
