1nwt: Difference between revisions
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{{STRUCTURE_1nwt| PDB=1nwt | SCENE= }} | {{STRUCTURE_1nwt| PDB=1nwt | SCENE= }} | ||
===Crystal structure of human cartilage gp39 (HC-gp39) in complex with chitopentaose=== | |||
{{ABSTRACT_PUBMED_12851408}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/CH3L1_HUMAN CH3L1_HUMAN]] A genetic variation in CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) [MIM:[http://omim.org/entry/611960 611960]]. Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea, bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CH3L1_HUMAN CH3L1_HUMAN]] Carbohydrate-binding lectin with a preference for chitin. May play a role in defense against pathogens, or in tissue remodeling. May play an important role in the capacity of cells to respond to and cope with changes in their environment.<ref>PMID:9492324</ref> | |||
==About this Structure== | ==About this Structure== | ||
| Line 14: | Line 16: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:012851408</ref><references group="xtra"/> | <ref group="xtra">PMID:012851408</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bos, E.]] | [[Category: Bos, E.]] | ||
