1qtt: Difference between revisions
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{{STRUCTURE_1qtt| PDB=1qtt | SCENE= }} | {{STRUCTURE_1qtt| PDB=1qtt | SCENE= }} | ||
===SOLUTION STRUCTURE OF THE ONCOPROTEIN P13MTCP1=== | |||
{{ABSTRACT_PUBMED_10959629}} | |||
== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/MTCP1_HUMAN MTCP1_HUMAN]] Note=Detected in T-cell leukemia bearing a t(X;14) translocation. Plays a key role in T-cell prolymphocytic leukemia. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MTCP1_HUMAN MTCP1_HUMAN]] Enhances the phosphorylation and activation of AKT1 and AKT2.<ref>PMID:10983986</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:010959629</ref><references group="xtra"/> | <ref group="xtra">PMID:010959629</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Guignard, L.]] | [[Category: Guignard, L.]] | ||
Revision as of 18:25, 24 March 2013
SOLUTION STRUCTURE OF THE ONCOPROTEIN P13MTCP1
Template:ABSTRACT PUBMED 10959629
Disease
[MTCP1_HUMAN] Note=Detected in T-cell leukemia bearing a t(X;14) translocation. Plays a key role in T-cell prolymphocytic leukemia.
Function
[MTCP1_HUMAN] Enhances the phosphorylation and activation of AKT1 and AKT2.[1]
About this Structure
1qtt is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Guignard L, Padilla A, Mispelter J, Yang YS, Stern MH, Lhoste JM, Roumestand C. Backbone dynamics and solution structure refinement of the 15N-labeled human oncogenic protein p13MTCP1: comparison with X-ray data. J Biomol NMR. 2000 Jul;17(3):215-30. PMID:10959629
