2rhp: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "2rhp" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_2rhp| PDB=2rhp | SCENE= }} | {{STRUCTURE_2rhp| PDB=2rhp | SCENE= }} | ||
===The Thrombospondin-1 Polymorphism Asn700Ser Associated with Cornoary Artery Disease Causes Local and Long-Ranging Changes in Protein Structure=== | |||
{{ABSTRACT_PUBMED_18499674}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/TSP2_HUMAN TSP2_HUMAN]] Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disk disease (IDD) [MIM:[http://omim.org/entry/603932 603932]]; also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain.<ref>PMID:18455130</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TSP2_HUMAN TSP2_HUMAN]] Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.<ref>PMID:20714802</ref> | |||
==About this Structure== | ==About this Structure== | ||
| Line 11: | Line 13: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:018499674</ref><references group="xtra"/> | <ref group="xtra">PMID:018499674</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Carlson, C B.]] | [[Category: Carlson, C B.]] | ||