2a41: Difference between revisions
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{{STRUCTURE_2a41| PDB=2a41 | SCENE= }} | {{STRUCTURE_2a41| PDB=2a41 | SCENE= }} | ||
===Ternary complex of the WH2 Domain of WIP with Actin-DNAse I=== | ===Ternary complex of the WH2 Domain of WIP with Actin-DNAse I=== | ||
{{ABSTRACT_PUBMED_16275905}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [[http://www.uniprot.org/uniprot/DNAS1_BOVIN DNAS1_BOVIN]] Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:016275905</ref><references group="xtra"/> | <ref group="xtra">PMID:016275905</ref><references group="xtra"/><references/> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Deoxyribonuclease I]] | [[Category: Deoxyribonuclease I]] | ||
Revision as of 19:51, 24 March 2013
Ternary complex of the WH2 Domain of WIP with Actin-DNAse I
Template:ABSTRACT PUBMED 16275905
Function
[ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [DNAS1_BOVIN] Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity).
About this Structure
2a41 is a 3 chain structure with sequence from Bos taurus and Oryctolagus cuniculus. Full crystallographic information is available from OCA.
See Also
Reference
- Chereau D, Kerff F, Graceffa P, Grabarek Z, Langsetmo K, Dominguez R. Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly. Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16644-9. Epub 2005 Nov 7. PMID:16275905
