3vq2: Difference between revisions

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~~[[Image:3vq2.jpg|left|200px]]~~

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~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~

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===Crystal structure of mouse TLR4/MD-2/LPS complex===

==Disease==

[[http://www.uniprot.org/uniprot/TLR4_MOUSE TLR4_MOUSE]] Note=The protein is encoded by the Lps locus, an important susceptibility locus, influencing the propensity to develop a disseminated Gram-negative infection.

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==Function==

~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_22532668}}~~, ~~adds the Publication Abstract~~ to the ~~page~~

[[http://www.uniprot.org/uniprot/TLR4_MOUSE TLR4_MOUSE]] Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).<ref>PMID:10952994</ref> [[http://www.uniprot.org/uniprot/LY96_MOUSE LY96_MOUSE]] Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS (By similarity).

(~~as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov~~), ~~where 22532668 is~~ the ~~PubMed ID number~~.

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~~{{ABSTRACT_PUBMED_22532668}}~~

==About this Structure==

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==Reference==

[[Category: Mus musculus]]

[[Category: Ohto, U.]]

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@@ Line 1: / Line 1: @@
-[[Image:3vq2.jpg|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3vq2", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3vq2|  PDB=3vq2  |  SCENE=  }}
 ===Crystal structure of mouse TLR4/MD-2/LPS complex===
+{{ABSTRACT_PUBMED_22532668}}
+==Disease==
+[[http://www.uniprot.org/uniprot/TLR4_MOUSE TLR4_MOUSE]] Note=The protein is encoded by the Lps locus, an important susceptibility locus, influencing the propensity to develop a disseminated Gram-negative infection.
-<!--
+==Function==
-The line below this paragraph, {{ABSTRACT_PUBMED_22532668}}, adds the Publication Abstract to the page
+[[http://www.uniprot.org/uniprot/TLR4_MOUSE TLR4_MOUSE]] Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).<ref>PMID:10952994</ref> [[http://www.uniprot.org/uniprot/LY96_MOUSE LY96_MOUSE]] Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS (By similarity).
-(as it appears on PubMed at http://www.pubmed.gov), where 22532668 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_22532668}}
 ==About this Structure==
@@ Line 22: / Line 13: @@
 ==Reference==
-<ref group="xtra">PMID:022532668</ref><references group="xtra"/>
+<ref group="xtra">PMID:022532668</ref><references group="xtra"/><references/>
 [[Category: Mus musculus]]
 [[Category: Ohto, U.]]