1p49: Difference between revisions
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{{STRUCTURE_1p49| PDB=1p49 | SCENE= }} | {{STRUCTURE_1p49| PDB=1p49 | SCENE= }} | ||
===Structure of Human Placental Estrone/DHEA Sulfatase=== | |||
{{ABSTRACT_PUBMED_12657638}} | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/STS_HUMAN STS_HUMAN]] Defects in STS are the cause of ichthyosis X-linked (IXL) [MIM:[http://omim.org/entry/308100 308100]]. Ichthyosis X-linked is a keratinization disorder manifesting with mild erythroderma and generalized exfoliation of the skin within a few weeks after birth. Affected boys later develop large, polygonal, dark brown scales, especially on the neck, extremities, trunk, and buttocks.<ref>PMID:1539590</ref><ref>PMID:9252398</ref><ref>PMID:10679952</ref><ref>PMID:10844566</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/STS_HUMAN STS_HUMAN]] Conversion of sulfated steroid precursors to estrogens during pregnancy. | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:012657638</ref><references group="xtra"/> | <ref group="xtra">PMID:012657638</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Steryl-sulfatase]] | [[Category: Steryl-sulfatase]] | ||
