2pho: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "2pho" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_2pho| PDB=2pho | SCENE= }} | {{STRUCTURE_2pho| PDB=2pho | SCENE= }} | ||
===Crystal structure of human arginase I complexed with thiosemicarbazide at 1.95 resolution=== | ===Crystal structure of human arginase I complexed with thiosemicarbazide at 1.95 resolution=== | ||
==Disease== | |||
[[http://www.uniprot.org/uniprot/ARGI1_HUMAN ARGI1_HUMAN]] Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:[http://omim.org/entry/207800 207800]]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.<ref>PMID:1463019</ref><ref>PMID:7649538</ref> | |||
==About this Structure== | ==About this Structure== | ||
| Line 10: | Line 9: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:017469833</ref><references group="xtra"/> | <ref group="xtra">PMID:017469833</ref><references group="xtra"/><references/> | ||
[[Category: Arginase]] | [[Category: Arginase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
