3e77: Difference between revisions
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{{STRUCTURE_3e77| PDB=3e77 | SCENE= }} | {{STRUCTURE_3e77| PDB=3e77 | SCENE= }} | ||
===Human phosphoserine aminotransferase in complex with PLP=== | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/SERC_HUMAN SERC_HUMAN]] Defects in PSAT1 are the cause of phosphoserine aminotransferase deficiency (PSATD) [MIM:[http://omim.org/entry/610992 610992]]. PSATD is characterized biochemically by low plasma and cerebrospinal fluid concentrations of serine and glycine and clinically by intractable seizures, acquired microcephaly, hypertonia, and psychomotor retardation.<ref>PMID:17436247</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SERC_HUMAN SERC_HUMAN]] Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
*[[Phosphoserine aminotransferase|Phosphoserine aminotransferase]] | *[[Phosphoserine aminotransferase|Phosphoserine aminotransferase]] | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phosphoserine transaminase]] | [[Category: Phosphoserine transaminase]] | ||
