1z83: Difference between revisions
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{{STRUCTURE_1z83| PDB=1z83 | SCENE= }} | {{STRUCTURE_1z83| PDB=1z83 | SCENE= }} | ||
===Crystal structure of human AK1A in complex with AP5A=== | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/KAD1_HUMAN KAD1_HUMAN]] Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency (HAAKD) [MIM:[http://omim.org/entry/612631 612631]].<ref>PMID:2542324</ref><ref>PMID:9432020</ref><ref>PMID:12649162</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KAD1_HUMAN KAD1_HUMAN]] Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. | |||
==About this Structure== | ==About this Structure== | ||
[[1z83]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z83 OCA]. | [[1z83]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z83 OCA]. | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Adenylate kinase]] | [[Category: Adenylate kinase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
