3l6y: Difference between revisions
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{{STRUCTURE_3l6y| PDB=3l6y | SCENE= }} | {{STRUCTURE_3l6y| PDB=3l6y | SCENE= }} | ||
===Crystal structure of p120 catenin in complex with E-cadherin=== | ===Crystal structure of p120 catenin in complex with E-cadherin=== | ||
{{ABSTRACT_PUBMED_20371349}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CTND1_HUMAN CTND1_HUMAN]] Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.<ref>PMID:17344476</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:020371349</ref><references group="xtra"/> | <ref group="xtra">PMID:020371349</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Ikura, M.]] | [[Category: Ikura, M.]] | ||
