3svf: Difference between revisions

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~~[[Image:3svf.jpg|left|200px]]~~

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===Crystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand===

===~~Crystal Structure of the first bromodomain of human~~ BRD4 in ~~complex~~ with a ~~dihydro~~-~~quinazolin ligand===~~

==Disease==

[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref><ref>PMID:11733348</ref>

==Function==

[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).

==About this Structure==

[[3svf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SVF OCA].

==Reference==

[[Category: Homo sapiens]]

[[Category: Arrowsmith, C H.]]

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-[[Image:3svf.jpg|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3svf", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_3svf|  PDB=3svf  |  SCENE=  }}
+===Crystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand===
+{{ABSTRACT_PUBMED_021851057}}
-===Crystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand===
+==Disease==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref><ref>PMID:11733348</ref>
+==Function==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
 ==About this Structure==
 [[3svf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SVF OCA].
+==Reference==
+<references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Arrowsmith, C H.]]